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Endocrine Abstracts (2024) 99 EP659 | DOI: 10.1530/endoabs.99.EP659

1Hospital General de Segovia (HGSE), Servicio de Endocrinología y Nutrición, Segovia, Spain; 2Hospital Clínico Universitario de Valladolid., Servicio de Endocrinología y Nutrición, Valladolid, Spain; 3Complejo Asistencial de Palencia. Hospital Rio Carrión, Servicio de Endocrinología y Nutrición, Palencia, Spain


Introduction: Hyponatremia is the most frequent disturbance in hospitalized patients. The appropriate treatment of non-severe hyponatremia according to the clinical guidelines is essential to achieve an effective response defined as eunatremia (Serum sodium >135 mmol/l). The aim of this study was to know the relationship between appropriate treatment and effective response in patients with enteral tube feeding (TEN).

Methods: An observational, prospective study during 24 months. The study was designed in non-critically hyponatremic patients receiving TEN and presenting hyponatremia. Data collected included sex, age, clinical volemia, type of treatment and serum sodium levels before, 72 hours and one week after started treatment.

Results: 87 patients were included, 62,1% males, age 76 (IR 67–84) years. 8,0% were hypovolemic, 86,0% were euvolemic and 6,0% were hypervolemic. 39 patients (44,8%) received appropriate treatment, in 100% hypovolemic, 83,3% euvolemic and 100% hypervolemic patients. Eunatremia was reached by 74%: 5,1% of hypervolemic; 64,1% of euvolemic patients and 5,1% in hypovolemic patients. The percentage of patients achieving eunatremia following one week was 38,4% and the median of time between hyponatremia diagnostic and the start of treatment was 3,0 [RIQ 3,9-14,0] days.

Conclusion: The appropriate treatment was established in almost half of the hyponatremic patients with TEN. An effective response was achieved in the majority of patients within a week of the beginning treatment.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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