Endocrine Abstracts

Introduction: For the past three years, patients with type 1 diabetes have been treated with basal-bolus therapy at the Axarquia Hospital by doctors from the Clinical Management Unit of Endocrinology and Nutrition at the Malaga Regional University Hospital. Treating patients in their own health area avoids travel and could have an impact on better follow-up, metabolic control, and the incidence of complications. The aim of this study is to describe the socio-demographic and clinical characteristics of the patients seen in this clinic.

Material and Methods: Cross-sectional descriptive observational study of patients with type 1 diabetes mellitus followed up at the Diabetes Clinic of the Axarquia Hospital. Data were obtained from their electronic medical records. The analysis was carried out using the JAMOVI programme.

Results: Data were collected from 335 people with type 1 DM. The mean age was 42.9±14.8 years (16-82). Forty percent were women. The mean BMI was 26.6±5.27 (15.1-51.1). 22.9% were smokers and 25.7% were ex-smokers. 25.8% had hypertension and 45.5% were on lipid-lowering therapy. 9.8% had diabetic nephropathy, 32.4% had diabetic retinopathy and 12.9% had diabetic neuropathy. The mean glycated haemoglobin was 7.70± 1.15. Regarding the glucose activity profile recorded by the intermittent glucose monitoring systems, sensor usage was 89.6±10.3%, mean glucose 174±38.9 mg/dl, glucose variability 37.6±7.65%, mean interstitial glucose (MIG) 7.49±0. 94%, time in range (70-180 mg/dl) 56.6±18.5%, time above range (181-250 mg/dl) 23.9±8.78%, time in very high range (> 250 mg/dl) 15.8±15.4%, time below range (55-69 mg/dl) 3.24±3.21% and time far below range (<54 mg/dl) 0.6±1.52%. Regarding basal insulin use, 48.2% used degludec, 49.3% used glargine U100 and the remaining 2.5% used a first-generation basal insulin analogue. For rapid insulin, 70.7% used Fiasp and the remaining 29.3% used rapid insulin analogues.

Conclusions: The Diabetes Unit of the Axarquia Hospital treats patients with complex characteristics and a high percentage of microvascular complications. It would be interesting to follow the long-term evolution of these patients and to analyse the impact of the care provided in the regional hospital on the achievement of glycaemic targets.