Endocrine Abstracts

Introduction: Papillary thyroid cancer is a cancer with a good prognosis and slow progression. Only 2 to 10% of distant metastases, the most frequent at the pulmonary level, cranial metastases represent 2.5 to 5.8% of cases. Renal metastases are extremely rare. We report a case.

Observation: 74-year-old patient, without suggesting, presents papillary thyroid carcinoma in its trabecular variant classified pT2NxM1, discovered following a left iliac metastasis. On extension assessment, CT-TAP: found a large left iliac lytic lesion measuring 68×57×71mm, A pulmonary hamartochondroma, bilateral cortical renal cysts including one suspected of malignancy, A harmonious thickening of the outer arm of the right adrenal 9mm and a left renal mass. A biopsy confirmed the secondary origin of the left iliac and renal masses. The patient received 200mci iratherapy, with post-therapeutic scanning of areas of hyperuptake in the left hemi-pelvis and the left renal compartment. Given the risk of bleeding from her left iliac mass, she underwent embolization before orthopedic surgery. Currently she has accumulated 800 mci of iodine with a good response.

Discussion: Renal metastases from differentiated thyroid carcinomas represent 2.5 to 2.7% of cases. Diffusion occurs mainly by the hematogenous route, more rarely by the lymphatic route.