ECE2024 Eposter Presentations Late Breaking (127 abstracts)
Malignant pheochromocytoma unmasked by paralyzing sciatic symptoms: a case report
Hasna Ouirar , Caimae Zouna , Ikrame Qasdi , Kaoutar Elmoatamid , Fatima Toulali , Ghizlane Sabbar , Kaoutar Rifai , Iraqi Hinde & Mohamed Elhassan Gharbi
Ibn Sina University Hospital, Endocrinology and Metabolic Diseases, Rabat, Morocco
Introduction: Developing in the adrenal medulla’s chromaffin cells, pheochromocytoma (PC) is an infrequent tumor Illustrating the instance of a patient diagnosed with malignant adrenal pheochromocytoma (PCM) following the onset of paralyzing sciatic pain
Case: A 60-year-old patient managing hypertension with triple therapy and type 2 diabetes using metformin and insulin glargine. The patient sought emergency care due to recurrent and disabling sciatic pain progressing to paraplegia. Concurrent constitutional symptoms, significant weight loss, and anorexia prompted a lumbar spine MRI, revealing spinal cord compression with an L3 fracture, and a concurrent 88mm adrenal mass, as further confirmed by an abdominopelvic CT scan. Secretory biochemical analysis indicated a significant increase in plasma Normetanephrines, measuring 116 times the normal level, while Metanephrines remained within the normal range. An 18F-FDG PET scan performed for staging purposes confirmed the hypermetabolic adrenal mass and identified a vertebral tumor extension with comparable features to the adrenal tumor. Surgical intervention has been advised after medical preparation.
Discussion: A neuroendocrine tumor, pheochromocytoma, is an infrequent condition marked by excessive catecholamine secretion. Malignancy is noted in 10% of cases, determined by metastases in tissues lacking chromaffin cells. It has a hereditary component in 40% of cases and in order to provide the best care, a coordinated, multidisciplinary approach is imperative
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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