Endocrine Abstracts

In the presented case, an 85-year-old female patient with bipolar disorder exhibited significant endocrine complications, including hyperparathyroidism and diabetes insipidus, which were strongly associated with long-term lithium therapy. The resolution of these complications following the discontinuation of lithium and the transition to an alternative mood stabilizer underscores several important clinical implications. Firstly, this case highlights the need for vigilant monitoring of elderly patients undergoing lithium therapy. Lithium-induced endocrine disturbances, although relatively uncommon, can manifest insidiously and have the potential to substantially impact the patient’s quality of life and overall health. Secondly, the observed reversibility of hyperparathyroidism and diabetes insipidus upon discontinuation of lithium underscores the importance of early intervention. Furthermore, the case highlights the significance of individualizing treatment plans for elderly patients with bipolar disorder. In this population, where comorbidities are prevalent and overall health is a paramount concern, clinicians should carefully weigh the benefits of lithium therapy against the potential risks, particularly those related to endocrine function. In conclusion, this case report sheds light on the reversible nature of lithium-induced hyperparathyroidism and diabetes insipidus in an elderly patient with bipolar disorder. It underscores the importance of vigilant monitoring, early recognition, and individualized treatment strategies to optimize the care of bipolar disorder patients, especially in older individuals, where preserving overall health becomes increasingly crucial. While lithium remains a valuable tool in the management of bipolar disorder, its potential adverse effects should be carefully considered, and alternative mood stabilizers explored when deemed appropriate for the patient’s well-being.