ECE2024 Eposter Presentations Thyroid (198 abstracts)
Subclinical hyperthyroidism: exploring etiologies, clinical profiles and outcomes
Baltagi Myriam 1 , Sawsen Essayeh 2 , Imen Rojbi 2 , Ibtissem Ben Nacef 2 , Sabrine Mekni 2 , Rihab Laamouri 2 & Karima Khiari 2
1Tunisia, Endocrinology, Tunisia; 2
Introduction: Subclinical hyperthyroidism (SH) is defined by normal thyroid hormone levels and reduced thyroid-stimulating hormone (TSH) concentration. It still raises intriguing questions about its clinical impact, management and outcomes. The aim of our study was to determine the underlying etiologies of SH, its clinical features and its outcomes in Tunisian patients.
Methods: We conducted a retrospective study at Charles Nicolle Hospital, including 46 patients with subclinical hyperthyroidism. Clinical data and paraclinical parameters were collected for analysis.
Results: The mean age of patients was 67±8 years, with a female predominance (26women against20 men). Patients were managing health conditions, including 60% with type 2 diabetes, 42% with hypertension, 56% with dyslipidemia, and 8% with coronopathy. The majority of diagnoses (49%) for subclinical hyperthyroidism were incidental, discovered through routine medical analyses. Hashitoxicosis emerged as the most prevalent etiology, accounting for 32%, followed by Graves’ disease at 21%, and multinodular goiter at 5%. In the majority of cases, the therapeutic decision involved a conservative approach, opting to monitor patients without initiating treatment. SH resolved spontaneously in 35% of cases.
Conclusion: In summary, our study emphasizes the importance of individualized approaches in addressing this condition, considering its varied etiologies and the potential for spontaneous resolution. Wait-and-See approach can be an interesting therapeutic alternative when hashitoxicosis is the suspected cause.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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