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Endocrine Abstracts (2024) 99 EP822 | DOI: 10.1530/endoabs.99.EP822

ECE2024 Eposter Presentations Thyroid (198 abstracts)

Preoperative biological markers in papillary thyroid carcinoma

Sameh Mezri 1 , Chaima Zitouni 1 , Wadii Thabet 2 , Salah Menasria 1 & Khemaies Akkari 1


1Principal Military Hospital, ENT, Tunis, Tunisia; 2Taher Sfar Hospital, Mahdia, Tunisia


Introduction: Carcinogenesis results from a disturbance in the balance between apoptosis and cell proliferation. This process involves inflammatory cells, which play a pro- and anticarcinogenic role.

Objective: the aim of this study is to investigate the status of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) as potential biomarkers in predicting the evolutionary profile of papillary thyroid cancers.

Methods: This is a retrospective study including 80 patients operated on for papillary thyroid cancer at our department between 2010 and 2019. We studied the predictive role of NLR and PLR in metastases, multifocal forms and recurrences.

Results: NLR and PLR were significantly higher in cases of extra-thyroidal invasion (P=0.04), multifocal tumours (P=0.01), locoregional or distant lymph node metastases (P=0.03); unlike gender, age, tumor size, histological subtype or TNM stage.

Conclusion: NLR and PLR are inexpensive and easy to perform. They can also predict the evolutionary profile of papillary thyroid cancers.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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