ECE2024 Eposter Presentations Thyroid (198 abstracts)
Primary thyroid lymphoma: experience of our department
El Omri Malika 1 , Jemli S 1 , Lazid Sarra 1 , Bellakhdher Mouna 1 , Meherzi Abir 1 , Houas Jihene 1 , Ghammem Monia 1 , Ach Taieb 2 , Kermani Wassim 1 & Abdelkefi Mohamed 1
1ENT department Farhat Hached hospital, Sousse, Tunisia; 2Endocrinology department Farhat Hached hospital, Sousse, Tunisia
Introduction: Primary thyroid non-Hodgkin’s lymphoma, which is defined as a lymphoma occurring in the thyroid gland, is a quite rare pathologic entity, accounting for 1, 3-1, 5 % of thyroid neoplasm, and 0, 5% of lymphoma. The aim of our work is to evaluate the clinicopathological features and treatment outcomes of patients with primary thyroid lymphoma.
Material and methods: We report 8cases of primary thyroid lymphoma collected at our department between 2000 and 2023.
Results: There were 6 women and two men with an average age of 63 years. One patient had a history of neoplasia of the right breast and adenocarcinoma of the colon. The reason for consultation was an anterior basicervical swelling in all patients associated with dysphonia in one patient, dysphagia in one patient, and dyspnea in three patients. The clinical examination revealed a huge painless goiter compressive in one patient, associated with bilateral lymph nodes in two patients, and ipsilateral in a patient. One patient had an emergency tracheotomy. Four patients had biopsy and the other four patients had thyroidectomy. Histological examination concluded to a mantle lymphoma in two cases, a diffuse large B-cell lymphoma in four patients, and a MALT lymphoma in two cases. Only one patient presented an invasion of the medullary bone confirmed by biopsy. All patients underwent chemotherapy. Three patients died and 4 patients presented no recurrence.
Conclusion: Primary thyroid lymphoma is an uncommon pathologic entity. The prognosis is primarily dependent on age, staging, and disease spread, then the histologic subtype.
Keywords: autoimmune thyroiditis, hypothyroidism, euthyroidism, genetic polymorphism.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more