ECE2024 Eposter Presentations Pituitary and Neuroendocrinology (214 abstracts)
Acromegaly revealed by unstable diabetes
Karimi Meryem 1 , Ali Halouache 2 , Isswani Jad 2 & Guerboub Ahmed Anas 2
1Ibn Sina Rabat, Endocrinology Rabat, Morocco; 2Hôpital Militaire D’Instruction Mohammed V, Endocrinology Rabat, Morocco
Introduction: Acromegaly is a rare condition characterized by the hypersecretion of growth hormone (GH), resulting in morphological anomalies, metabolic disturbances, including overt diabetes, and endocrine abnormalities.
Case Report: We present the case of a 54-year-old patient with a history of cervical lumbar sciatica under treatment. The disease history dates back 3 years with the onset of polyuria-polydipsia syndrome and fatigue. On clinical examination, the patient exhibits acrofacial dysmorphic features. The laboratory findings revealed an HbA1c of 8%, IGF1 level twice the normal range. Hypothalamo-hypophysial MRI reveals a 12 mm pituitary macroadenoma without invasion of the cavernous sinuses. The patient was prescribed oral antidiabetic drugs and subsequently referred to a neurosurgeon for surgical intervention.
Discussion and Conclusion: Acromegaly is an insidious and slowly progressive pathology, often leading to a late diagnosis. This prolonged diagnostic delay is responsible for the onset of complications, including diabetes.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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