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Endocrine Abstracts (2024) 99 EP1081 | DOI: 10.1530/endoabs.99.EP1081

ECE2024 Eposter Presentations Pituitary and Neuroendocrinology (214 abstracts)

Medullary thyroid microcarcinoma revealed by lymph node metastases. about a case

Karimi Meryem 1 , Hajar Azagouagh 1 , Nawal Moussaid 1 , Rifai Kaoutar 1 , Iraqi Hind 1 & Mohamed Elhassan Gharbi 1


1Chu Ibn Sina, Endocrinology Rabat, Morocco


Introduction: Micro medullar, thyroid carcinoma is defined as a rare variant of MTC, with a size less than or equal to 1 cm, often incidentall, discovered.

Observation: A 67-year-old patient with no medical history presented with two supraclavicular lymph nodes four years ago. A biopsy revealed metastatic tumor proliferation suggestive of a carcinomatous process. Immunohistochemistry confirmed cervical lymph node metastasis of MTC, and further testing showed a calcitonin level of 10,769 ng/ml. A PET SCAN revealed no anomalies, and a thorough evaluation for multiple endocrine neoplasia (MEN) was normal. Total thyroidectomy with bilateral extensive lymph node dissection was performed, revealing a 5mm intraparenchymal low-grade micro medullary carcinoma.

Discussionl and Conclusion: Contrary to the common perception of micro medullary thyroid carcinoma as having a favorable prognosis, a significant increase in the prevalence of lymph node metastases is observed. Due to the severity of complications associated with recurrences and distant metastases, two approaches are utilized: regular monitoring of serum calcitonin levels, showing a decreasing trend, and genetic screening, particularly in hereditary cases. Biochemical screening programs are crucial for identifying sporadic cases of micro medullary thyroid carcinoma in patients with thyroid nodules.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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