Endocrine Abstracts

Metabolic syndrome (MS) is a widespread clinical syndrome, the incidence of which is increasing annually in both developing and developed countries. The prevalence of MS among the working population is quite high (20-25%) and tends to increase. The presence of MS increases the risk of developing type II diabetes and cardiovascular diseases, and anxiety and depression are considered as independent risk factors for the development of MS. It has also been found that the prevalence of anxiety is approximately 10% higher among the group of patients with MS compared to those without MS.

Purpose: to study the psycho-emotional status in patients with metabolic syndrome.

Methods: This study was conducted at the clinic of the Scientific Research Institute of Medical Problems of the North. Inclusion criteria: age (20-60 years); absence of mental, infectious and chronic somatic diseases in the stage of decompensation. All patients were divided into 2 groups: 1) group No. 1 - 76 patients with MS, 2) group No. 2 - 42 practically healthy volunteers who had no concomitant diseases and were not obese. The patients were examined and anthropometric parameters were determined: waist circumference (cm), body weight (kg), BMI (kg/m²;). The assessment of quality of life (QOL) was determined using the questionnaire «SF-36». The assessment of the psycho-emotional status of patients was carried out using a questionnaire: HADS.

Results: in the course of our study, we found that according to the SF-36 questionnaire, QOL indicators were statistically significantly different in the group of patients with MS relative to the group of patients without MS. Thus, indicators of the level of quality of life are significantly higher in healthy individuals than in obese patients. The differences in all groups are significant (P≤0.05). It was also found that the average level of parameters on the scale ‘physical functioning’ decreased by 19.7% (P<0.05), ‘role functioning’ by 35.2% (P<0.05), ‘general health’ by 15, 1% (P<0.05), ‘vitality’ by 18% (P<0.05), ‘emotional functioning’ by 53.1% (P<0.05). The assessment of the level of anxiety and depression in patients with MS corresponded to a subclinically expressed level, and the level of depression exceeded the indicator in group No. 2 by 19.3%. The level of quality of life in obese patients is significantly lower than in healthy individuals.

Conclusion: The results obtained show that the patterns established in this study should be taken into account when carrying out preventive measures among patients with MS.