Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is primarily diagnosed through biological analyses. Modern imaging, particularly ultrasound and scintigraphy, plays a crucial role in localizing parathyroid adenomas.

Methods: A retrospective analysis of 132 patients with PHPT from the endocrinology-diabetology department at Ibn Rochd Hospital Casablanca, including cervical ultrasounds and parathyroid scintigraphy. Computed tomography (CT) and MRI are used as secondary resources. To have the below statistics we used SPSS software.

Results: In this studied population, the average age is 53.4 years, with a clear female predominance (85.93%). Biological examinations showed elevated levels of calcium and phosphorus, averaging 114.93 mg/l and 22.20 mg/l respectively. The average PTH level was also high, reaching 830.56 pg/ml. The majority of patients (71.87%) reported bone pain, and 23.43% were diagnosed with kidney stones. In terms of imaging, ultrasound detected parathyroid adenomas in 64.06% of patients, while scintigraphy revealed hyperfixation in 85.93% of them. CT confirmed the presence of parathyroid adenomas in 64% of cases, with hyperplasia in 6.25% and parathyroid carcinomas in 1% of cases. Additionally, vitamin D deficiency was observed in 67% of patients.

Conclusion: Cervical ultrasound appears to be more effective than parathyroid scintigraphy in the topographic diagnosis of PHPT. CT and MRI are recommended in cases of discordant results or for atypical localizations.