Endocrine Abstracts

The military conflict in Ukraine triggered the internal migration of millions of Ukrainians. Internally displaced persons (IDPs) and residents of territorial communities (RTCs) located in zones of war with Diabetes mellitus (DM) are at high risk of developing post-traumatic stress disorder (PTSD), anxiety and depression.The aim of the study was to assess the health-related quality of life (HRQoL) of patients with DM type 1 (DM T1) and type 2 (DM T2) in the context of military conflict.

Materials and methods: 26 patients with DMT1 ((34.7±8.79) yrs, disease duration (DD) (11.0±10.5) yrs) and 65 patients with DMT2 ((56.5 ±10.79) yrs, DD (6.9±5.1) yrs) were examined. 43.9% (n=40) were IDPs and 56.1% (n=51) RTCs located in the war zone. The Ukrainian-language version of the "SF-36®Health Survey" questionnaire was used to assess the health care system. Subjective feelings of patients were analyzed using the HADS Hospital Anxiety and Depression Assessment Scale. Statistical processing of the results was performed using Package for Social Sciences v.16.0 (SPSS Inc, Chicago, Il, USA).

Results and discussion: It was found that the physical activity of patients with DM was significantly limited by their health status. Patients with DM T1 rated their general health status higher on the ‘general health status’ scale than patients with DMT2. In patients with DMT2, the average score on the ‘mental health’ scale was significantly lower than in patients with DMT1, which indicated the possible development of PTRs. It was determined that the physical activity of MTG-patients is significantly limited by their health status compared to the IDPs group. Assessment of the severity of depressive symptoms on the HADS-D subscale showed that in 46.2% (n=42) of the examined the total score was within the normal range, in 24.2% (n=22) it corresponded to subclinical depression and in 29.7% (n=27) – clinically significant depression. The total score on the HADS-D subscale in MTG-patients is significantly higher than in the IDPs group ((7.81±0.34) and (4.86±0.29), respectively; P< 0.04).

Conclusion: In conditions of war conflict, patients with DMT2 compared to patients with DMT1 experienced a more significant deterioration in PCH and mental component of health (MCH). MTH-patients with DM due to the deterioration of PCH and MCH, have more significant restrictions in daily activities, social contacts, and a decrease in the level of communication than IDPs. 53.9% of patients with DM in the conditions of a military conflict develop clinical depression of varying severity, 50.6% - clinical anxiety.