ECE2024 Eposter Presentations Calcium and Bone (102 abstracts)
Assessment of vitamin d status in patients with primary hyperparathyroidism: implications for clinical management
Gorgi Khaoula 1 , Errahali Yassine 2 , Echchad Lamya 1 , Rifai Kaoutar 1 , Iraqi Hinde 1 & Gharbi Mohamed El Hassan 1
1Ibn Sina University Hospital, Endocrinology, Rabat, Morocco; 2Mohamed V Military training hospital, Endocrinology, Rabat, Morocco
Introduction: Primary hyperparathyroidism is frequently accompanied by low vitamin D levels. This study aims to assess the vitamin D status of patients diagnosed with primary hyperparathyroidism, with a focus on determining the prevalence of insufficient and deficient 25(OH) D levels in this patient population.
Patients and Methods: Conducted as a retrospective study over a 7-year period (2015-2022), our research was carried out at the endocrinology-diabetology department of CHU IBN SINA RABAT and the Mohamed V military hospital in Rabat. The study concentrated on patients hospitalized for primary hyperparathyroidism, analyzing their vitamin D levels.
Results: A total of 63 patients, with an average age of 55.8 years, were included in the study. Systematic measurement of vitamin D levels revealed a mean serum 25(OH)D level of 19.20 ng/ml. Notably, 18% of patients had vitamin D insufficiency, while 60.7% exhibited vitamin D deficiency. In patients with low vitamin D, the average serum calcium was 121.8 mg/l, and the mean parathyroid hormone (PTH) level was 261.7 ng/ml. Patients with insufficient vitamin D displayed higher PTH and blood calcium levels compared to those with normal vitamin D levels.
Discussion/Conclusion: Primary hyperparathyroidism is commonly associated with vitamin D deficiency, resulting in more pronounced bone damage and a significant elevation in blood calcium and parathyroid hormone levels. This study emphasizes the importance of vitamin D supplementation in individuals with primary hyperparathyroidism who have deficient or insufficient 25(OH)D levels.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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