ECE2024 Eposter Presentations Adrenal and Cardiovascular Endocrinology (155 abstracts)
Clinical, biological and anatomopathological profile of pheochromocytomas
Marwa El Arem 1 , Bilel Ben Amor 1 , Ekram Hajji 1 , Sana Abid 1 , Ines Bayar 1 , Héla Marmouch 2 , Hanene Sayadi 2 & Inès Khochteli 3
1Hospital Fatouma Bourguiba, endocrinology, Monastir, Tunisia; 2Hospital Fatouma Bourguiba, endocrinology, Monastir; 3Hospital Fatouma Bourguiba, endocrinology
Introduction: Pheochromocytoma is a rare tumour of the adrenal medulla. The aim of our work is to describe the clinical, biological and anatomopathological profile of pheochromocytomas.
Material and method: Retrospective descriptive study carried out in the endocrinology department of the Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Results: Analysis of a series of 13 cases found 9 women and 4 men with an average age of 55.3+/-11 years, 12 patients were hypertensive, 46% of whom had paroxysmal hypertension. The circumstances of discovery were mainly suggestive symptoms (n=8), an adrenal incidentaloma (n=4) and resistant hypertension (n=1). The symptoms described were a Menard’s triad (61%), abdominal pain (23.7%) and weight loss (15.3%). The nosological setting was NF1 in two cases and VHL syndrome in one case. The topographical diagnosis was made by abdominal MRI (n=5), abdominal CT (n=5) and MIBG scintigraphy (n=2) with an average size of 5 cm. Methoxylated derivatives were elevated in all patients with a majority increase in normetanephrines with an average level 12 times normal.
Conclusion: The clinical presentation of pheochromocytoma is variable. It should be considered in the presence of any adrenal incidentaloma and resistant hypertension and/or associated with hypokalaemia.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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