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Endocrine Abstracts (2023) 94 P330 | DOI: 10.1530/endoabs.94.P330

SFEBES2023 Poster Presentations Bone and Calcium (41 abstracts)

Retrospective audit on biochemical, radiological investigations done prior to Parathyroidectomy for Primary Hyperparathyroidism

Sheethal Kumar , Emad Abdulrahim , Andrada Elena-Singh , Bethany Jones , Rajveer Chauhan , Basavaiah Natesh , Christopher Harrold , David Howe & C Pratibha Machenahalli


UHCW, Coventry, United Kingdom


As per NICE guideline, referral for parathyroidectomy need to be according the below, • symptoms of hypercalcaemia or • End-organ disease (renal stones, fragility fractures or osteoporosis) or • An albumin-adjusted serum calcium level of 2.85 mmol/litre or above.

Methods: We conducted a retrospective analysis of investigations done as per recommendation of NICE guidelines for patients who underwent Parathyroidectomy under the care of 2 parathyroid surgeons at UHCW between 2017 to 2022. Data was collected from the hospital database. Data analysed using Microsoft excel.

Results: 13 patients had recurrence following the parathyroidectomy (some of these patients were refereed from different hospitals).

Demographics:Gendernumber, %
Female n= 126, 72%
malen= 48, 28%
Biochemical analysis:
Calcium (mmol/l)>=2.5<2.5not done
n=163, 93%n=10, 5%n=2, 1%
PTH ( pmol/l)>=6.9<6.9not done
n=144, 82%n=2.9, 16%n=2, 1%
Vitamin D (nmol/l)>50<50not done
n=94, 53%n=58, 33%n=14, 8%
Phosphate (mmol/l)donenot done
n=94, 53%n= 81, 46%
Random urine calcium:creatinine clearance ratiodonenot done
n=77, 44%n=98, 56%
24h urine calcium donenot done
n= 76, 43%n=99, 56%
Imaging:
Ultrasound parathyroiddonenot done
n= 159, 90%n= 16, 10%
MIBIdonenot done
n=151, 86%n=24, 24%
4D CT donenot done
n=29, 16%n=149, 83%
Renal tract USSdonenot done
n=89, 50%n=86, 49.9%
DEXADONEnot done
n=137,78%n=38, 21%
normal n=29,
abnormal n= 108

Discussion: In this retrospective audit more than half of the cohort had not been screened for urine calcium excretion to exclude familial hypocalciuric hypercalcemia and 50% didn’t had ultrasound of the renal tract. Although 98.3% patients had confirmed histology, all investigations should be performed as per NICE guidelines before undergoing a parathyroidectomy.

Volume 94

Society for Endocrinology BES 2023

Glasgow, UK
13 Nov 2023 - 15 Nov 2023

Society for Endocrinology 

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