SFEBES2023 Basic Science Workshop Sessions Getting it right first time – experimental design (3 abstracts)
Basic Science Workshop 1 – Getting it right first time – experimental design: Accounting for circadian rhythms
University of Manchester, Manchester, United Kingdom
Most endocrinologists are aware of biological rhythms. As undergraduates, we might learn about the menstrual cycle in humans, seasonal changes in reproductive physiology in many animal species, and the circadian and ultradian patterns of cortisol secretion. In recent decades, research has started to uncover the full scope of the circadian clock’s influence on physiology (and pathophysiology). It is increasingly clear that we need to account for this in experimental design. In this workshop, I will discuss examples of how time of day can influence the results of sampling or interventions, in both human and animal studies. I will also talk about strategies to standardise practice, and how doing so can yield more meaningful data.