Endocrine Abstracts

Ageing is an inevitable biological process that affects all aspects of human physiology including reproductive health. While much attention has been devoted to the age-related decline in female fertility, the impact of ageing on male reproduction is perhaps less well appreciated. This presentation aims to provide a concise overview of the relationship between ageing and sperm health, highlighting key findings and implications. Ageing has a significant impact on sperm health an...

The advances in cancer therapy over the past two decades have led to remarkable improvements in survival rates, but treatments such as chemotherapy, radiotherapy and/or surgery can induce premature ovarian insufficiency (POI) in some circumstances. Fertility preservation (FP) is therefore a key challenge for these women. At diagnosis, all women affected by cancer should benefit from an informed consultation on the threat of compromising their fertility with planned cancer trea...

Menopause timing is highly variable, having a direct effect on reproductive lifespan, fertility and health outcomes in later life. Endocrine and imaging tests only record changes in ovarian function that have already taken place, thus disabling early prediction and identification of women with reduced reproductive lifespan. Human genetic studies have attempted to overcome this problem by identifying genetic markers associated with menopause timing and fertility. Using data fro...