SFEBES2023 Poster Presentations Thyroid (63 abstracts)
Link between thyroidectomy and the development of osteoporosis in a south american population
Luis Dulcey 1 , Juan Theran 2 , Jaime Gomez 1 , Edgar Blanco 1 & Maria Ciliberti 1
1Bucaramanga University, Bucaramanga, Colombia. 2Santander University, Bucaramanga, Colombia
Introduction: Patients undergoing thyroidectomy could be subject to osteoporosis, therefore, we evaluated the potential for fractures among 123 men and 134 controls from a South American hospital between 1999-2018.
Materials and methods: The influence of thyroidectomy on the incidence of fractures was evaluated using basic methods of analysis. In the primary analysis, the frequency of fractures in the operated cases was directly compared with that of the controls. The proportion of cases and controls with fractures prior to the index date was compared using the McNemar test.ResultsWith 2,204 person-years of follow-up in each group, survival free of any fracture of the vertebra, proximal humerus, distal forearm, pelvis, or proximal femur was similar in the two groups (P=0.31), and the relative risk of any of these fractures for thyroidectomized patients vs their controls increased by 1.8-fold (95% CI, 0.5–2.9).
Conclusion: The difference is fully explained by a statistically significant excess of proximal femoral fractures in men with thyroidectomy. Risk factors included older age at surgery and greater extent of surgery. It is pertinent to carry out this type of study in Latin American populations given the scarcity of literature in this regard.
DECS/MESH: Surgery, thyroid, osteoporosis.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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