Endocrine Abstracts

Introduction: Phosphatase and tensin homolog gene (PTEN) gene encodes a lipid phosphatase that plays a central role in cell-cycle processes. PTEN hamartoma tumour syndrome (PHTS), caused by the mutation of the PTEN gene, is a diverse multi-system disorder. PHTS is characterised by the hamartomatous growths, increased risk of breast, thyroid, and renal cancers. In terms of thyroid presentation of PHTS, there is up to 75% risk of multinodular goitre and the life...

Background: Undifferentiated pleomorphic sarcoma (UPS) of the thyroid is rare. It is often identified in its advanced stage, with distant metastasis, and has poor prognosis. This paper presents one of the less than 30 cases that have been documented ever since it was first identified in 1989. In the Philippines, there is no published report of a primary thyroid sarcoma.Case Presentation: The author describes a 73-year-ol...

Background: Graves disease is an autonomous condition characterised by interaction of the TSH receptor with autoantibody(TRAb). It is well recognised that atrial fibrillation (AF) is a consequence of hyperthyroidism but the prevalence, predictors and outcomes of AF in patients with Graves hyperthyroidism is not completely known.Method: We analysed a prospective database of Graves disease patients over a 16 year period fr...

Background: CT Angiography (CTA) is a frequently used modality of imaging for assessment and diagnosis of patients presenting with acute stroke. There is a paucity of data on management guidelines for the presence of incidental thyroid nodules found on CT Angiography in patients presenting with acute stroke.Methods: A retrospective analysis was conducted on 2092 patients presenting with acute stroke, identified through t...