Endocrine Abstracts

Primary aldosteronism (PA) or Conn’s syndrome is a condition in which one or both adrenal glands produce aldosterone in excess, independent of the normal renin-angiotensin-aldosterone system (RAAS) such that renin is typically suppressed and aldosterone is non-suppressible by sodium loading. This excessive and autonomous production of aldosterone causes hypertension, sodium retention, cardiovascular damage, increased potassium excretion that, if prolonged and severe, may ...