ETA2023 Poster Presentations Treatment 1 (9 abstracts)
1Asan Medical Center, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea, Radiology, Seoul, Korea, Rep. of South; 2Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Asan Medical Center, Radiology, Seoul, Korea, Rep. of South; 3Asan Medical Center, Asan Medical Center, Surgery, Seoul, Korea, Rep. of South; 4Asan Medical Center, University of Ulsan College of Medicine, Asan Medical Center, Pathology, Seoul, Korea, Rep. of South; 5University of Ulsan College of Medicine, Asan Medical Center, Asan Medical Center, Seoul, Korea, Rep. of South
Objective: To evaluate the effectiveness and safety of ultrasound-guided RFA for symptomatic distant metastasis of DTC.
Methods: The medical records of 12 patients who underwent RFA for palliative treatment of 18 symptomatic distant metastases from thyroid cancer between January 2008 and December 2020 were analyzed. All patients were assessed for their degree of discomfort, and were evaluated periodically as outpatients, clinically, and by imaging and serologic markers.
Results: Of the 18 tumors treated, 9 were soft tissue metastases, and 9 were bone metastases. The mean size of the treated tumor was 5.3 cm (range, 1.7-10.7 cm). All patients had complaints of pain and/or bulging before RFA. After RFA, the patients reported a subjective improvement in symptoms related to 11 out of the 18 metastatic tumors (61.1%). Nine out of 18 tumors decreased in size with a mean SRR of 0.43% ± 0.22%. There were no major complications during the treatment or follow-up period related to RFA. After a mean follow-up duration of 37.4 months, 5 patients had progression of the tumor, 4 patients had a stable tumor status, and 3 patients died due to pneumonia.
Conclusions: RFA can be used as palliative therapy to relieve the symptoms caused by metastatic tumors; however, it has a limited role in improving the overall prognosis in patients with distant metastasis from thyroid cancers.