Endocrine Abstracts

Introduction: Fine needle aspiration cytology(FNAC) is the mainstay for evaluation of nodular thyroid disease. Internationally reported prevalence for Bethesda I(unsatisfactory sample) category is 5-60%. Several factors may determine this result, including patient and nodules’ features as well as both FNAC performer and pathologists’ skills. Few studies have evaluated pre-procedure factors associated with unsatisfactory cytology results. If present, recognizing these...

Introduction: Paired box gene 8 (PAX8) is a key transcription factor required both for normal fetal thyroid development and maintenance of the differentiated thyroid phenotype, mediating transcriptional activation of SLC5A5, TG, and TPO, and synergizing with NKX2-1 at the TG promoter. Heterozygous PAX8 mutations are a rare but well-recognized cause of congenital hypothyroidism (CH) due to thyroid dysgenesis (TD), and are classically associated with thyroid hypoplasia. However,...

Purpose: To evaluate the association between ultrasonography (US) feature of thyroid gland and thyroid function in pediatric and adolescent populations with autoimmune diffuse thyroid diseases (AITD).Methods: From 2000 to 2020, we reviewed thyroid ultrasound (US) images and thyroid function statuses in 133 children and adolescent AITD patients. Our review of the images focused on decreased echogenicity and heterogeneity, which were classified into four g...

Objectives: 18F-choline PET/CT is a recently introduced imaging modality to localize hyperfunctioning parathyroid glands in patient with hyperparathyroidism. But there has been no study according the diagnostic power of 18F-choline PET/CT in Korea so far owing to its limited distribution. Therefore, we evaluated the diagnostic performance of 18F-choline PET/CT in detection of hyperfunctioning parathyroid gland in patients with primary hyperpara...

Objective: Patients with thyroiditis often have sialadenitis. Radioactive iodine therapy (RAIT) sialadenitis could lower the patient’s quality of life. However, it had not been investigated about the occurrence of RAIT sialadenitis and the presence of underlying thyroiditis. Therefore, we analyzed the preoperative thyroid ultrasound (US) with radiomics to figure out the occurrence of the RAIT sialadenitis.Materials and Methods: In this retrospective...

Background: Widespread use of imaging has led to the detection of an increasing number of thyroid nodules. Thyroid societies have recommended the use of Thyroid Imaging, Reporting and Data System (TIRADS). However, there is a multitude of such risk stratification systems (RSS) for selecting thyroid nodules for FNA. They may be time consuming and consensus on thyroid nodule descriptors lacks. Also studies have suggested that operators’ experience may not be inferior to usi...

Introduction: Positron emission tomography - computed tomography (PET-CT) is a highly sensitive imaging modality for evaluating a variety of conditions, including detection of cancer and potential metastases. PET-CT positive thyroid lesions are found incidentally in about 2.5 % of the scans. They can be focal or diffuse and as they pose a considerably high risk of malignancy further diagnostic tests such as neck ultrasound and fine-needle aspiration biopsy (FNAB) are recommend...

Objective: Beta thalassemia is associated with a number of endocrinopathies. Iron overload is thought to be at the root of thalassemia-related endocrinopathies, including hypothyroidism; however, morphologic changes that could be attributable to iron deposition in the thyroid gland have been under investigated. This study aims to evaluate thyroid gland volumes and stiffness in thalassemia patients using shear-wave ultrasound elastography (SWE), and to analyze if there is any r...

Objective: Some patients with Graves’ disease (GD) respond faster to antithyroid drugs (ATD) than others. Our aim was to study if levels of autoantibodies to the TSH-receptor (TRAb), thyroid-stimulating immunoglobulin (TSI), thyroid peroxidase antibodies (anti-TPO) and/or clinical factors influence the early response to anti thyroid drugs (ATD) in women with GD.Methods: This was a longitudinal cohort study of 65 women with GD and fT4 ≥50 pmol/...