Endocrine Abstracts

Background: The concept of collaborative thyroid care clinics (or networks), have been established over the last two decades, in many parts of the world.Objective: What are the main available components of collaborative community-based integrated thyroid programs in the Mississauga-Halton regions [West Greater Toronto Area (GTA), Ontario, Canada], that can provide opportunities for streamlining thyroid care?Method: Reviewing the av...

Objectives: We previously reported the outcome of 1-year follow-up of 2013 DTC patients in the DTCC (differentiated thyroid cancer in China) 1st stage Study. Using the retrospectively gathered information, we sought to observe the long-term follow-up and prognosis of these patients with DTC undergoing thyroid surgery.Methods: This multicenter, noninterventional study was conducted at eight tertiary hospitals across China. Data from the patient...

Aim: The assessment of the disease course and selected clinicopathological factors associated with recurrence risk and the effectiveness of surgical treatment of PTC patients.Material and Methods: The retrospective analysis of 260 PTC patients selected from 403 patients operated on for recurrent thyroid cancer between 2002 and 2018 was performed. All statistical analyses were done using the programming environment R (v. 4.0.2).Resu...

Introduction: Total thyroidectomy (TT) plus central neck compartment (CC) lymphnode dissection is still the recommended initial gold standard treatment for medullary thyroid cancer (MTC), even in the absence of a pre-surgical positive neck US evidence of lymphnode metastases. Considering the risk of surgical complications of this prophylactic surgery and the low rate of histologic finding of CC lymphnode metastases, a more tailored lymphnode’ surgery should be proposed. A...

Background: Patient decision aids (PtDAs) are structured clinical tools that facilitate shared decision making. Two important treatment decisions for patients with differentiated thyroid cancer (DTC), which could benefit from PtDAs, are: 1) the extent of surgery decision in patients with low-risk DTC and 2) the decision to start or delay starting the treatment with Tyrosine Kinase Inhibitors (TKIs) in patients with advanced tumors.Material and methods: P...

Introduction: The association between papillary thyroid carcinoma and thyroiditis was first reported in 1955 by Daily, in 2023 if this association is well established, it still continues to be talked about. Does cancer precede thyroiditis or does thyroiditis induce cancer and when the two combine does cancer have a better prognosis?Material and methods: We report a prospective study carried out in a hospital center in Algeria between 2020 and 2022 which ...

Background: According to the statistics of the Ministry of Health of Ukraine, before the accident at the Chernobyl nuclear power plant, the incidence of thyroid cancer in children under 14 years of age was on average 0.04 per 100,000 children, however long-term consequences of the accident have not been analyzed.Material and methods: We studied the incidence of thyroid cancer during the last 35 years in Ukraine in children under the age of 14 and 18 y.o....

Background: Hypertension (HTN) is the most frequent adverse event during treatment with Lenvatinib (LEN) for advanced Radioactive Iodine-Resistant Thyroid Cancer (RAI-R TC), but data on its best therapeutic management are limited.Objectives: To assess incidence, features and best management of LEN-related HTN in a consecutive single tertiary-care Centre.Methods: Evaluation included 29 patients treated with LEN, followed for a mean ...

Introduction: Anaplastic thyroid carcinoma (ATC) carries an extremely poor prognosis. The reported median survival time is 3-9 months and one year survival rate is 18-20%. Here we report 4 cases of ATC.Case reports: Case 1: An 82 year-old female presented with rapidly progressive anterior neck swelling. She underwent hemi-thyroidectomy and D1 dissection. Pathological diagnosis was ATC, T4aN0. External beam radiotherapy (EBRT) to the whole neck was admini...