Miscellaneous 2

ea0092ps2-11-01 | Miscellaneous 2 | ETA2023

Temporal pattern of thyroid function changes in patients with cured and not cured adrenocorticotropin (ACTH)-Dependent Hypercortisolism

Paola Giuseppe , Alessi Ylenia , Giovinazzo Salvatore , Giuffrida Giuseppe , Casablanca Rosalinda , Ragonese Marta , Certo Rosaria , Ferrau Francesco , Cannavo Salvatore , Moleti Mariacarla

Context: Chronic hypercortisolism is known to impact the hypothalamus-pituitary-thyroid (HPT) axis, through a disruption of both thyrotropin-releasing-hormone and thyroid-stimulating hormone (TSH) release. These changes, in turn, are responsible for reduced triiodothyronine (T3) and thyroxine (T4) synthesis and secretion, eventually resulting in central hypothyroidism (C-Hypo). However, data on magnitude and timing of recovery of the above abnormalities are still controversial...

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ea0092ps2-11-02 | Miscellaneous 2 | ETA2023

Resistance to thyroid hormone alpha: outcomes of twelve years of thyroxine therapy

Moran Carla , Vargha-Khadem Faraneh , Clark Chris , Seunarine Kiran , Muntoni Francesco , Bethlehem Richard , Lindley Keith , Watson Laura , Lyons Greta , Dattani Mehul T. , Chatterjee Krishna

Objectives: In 2011, we described the first case of Resistance to Thyroid Hormone due to a mutation in thyroid hormone receptor a (RTHα) in a six year old child with features of congenital hypothyroidism but near-normal thyroid function tests. Here, we report outcomes following twelve years of thyroxine therapy in this patient.Methods: Colonic contractility, intestinal transit time, growth, resting energy expenditure, heart rate and biochemical para...

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ea0092ps2-11-03 | Miscellaneous 2 | ETA2023

Evaluation of advanced end glycation products (AGES), their solube receptors (SRAGE) and the components of oxidative stress in patients with hashimoto’s thyroiditis on levothyroxine substitution

Csiha Sara , Molnar Istvan , Halmi Sandor , Hutkai David , Lorincz Hajnalka , Somodi Sandor , Katko Monika , Harangi Mariann , Paragh Gyorgy , Nagy Endre V. , Bodor Miklos , Berta Eszter

Background: Advanced glycation end products (AGEs) are heterogenous group of irreversible chemical moieties originated from non-enzymatic glycation and oxidation of proteins, nucleic acids, and lipids. The engagement of AGEs with their chief cellular receptor (RAGE) activates signaling pathways contributing to the progression of chronic diseases like autoimmune thyroiditis, type 2 diabetes mellitus and its complications. Soluble RAGE (sRAGE) prevents AGE-RAGE interaction in a ...

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ea0092ps2-11-04 | Miscellaneous 2 | ETA2023

Behavior of thyroid function tests in a brazilian elderly population using big data

Izabel Chiamolera Maria , Fernandes Ramalho Rodrigo , Ferrer Claudia , Viana Lima Jr Jose , Saddi Pedro , Gilberto H Vieira Jose , Maciel Rui , Paula Biscolla Rosa

Behavior of thyroid function tests in a Brazilian elderly population using Big DataIntroduction: Interpretation of thyroid function data has changed over the last decades with several groups demonstrating changing in the thyroid axis with aging, particularly with a progressive increase in age-related TSH. With the proliferation of studies with large datasets, termed Big Data, sample sizes are no longer a challenge, and the possibility of using clinical l...

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ea0092ps2-11-05 | Miscellaneous 2 | ETA2023

Sensitivity to thyroid hormones and cardiometabolic risk in euthyroid obese children: A cross-sectional study

Wasniewska Malgorzata , Tropeano Angelo , Corica Domenico , Li Pomi Alessandra , Alibrandi Angela , Pepe Giorgia , Aversa Tommaso

Background: The typical biochemical phenotype related to obesity, that is high serum TSH within normal range, low/normal free thyroxine (FT4) and increased free triiodothyronine (FT3) levels, can be interpreted as a resistance to thyroid hormones. It is unclear the role played by thyroid hormones in the pathogenesis of metabolic derangement associated with obesity. Aim: To investigate the association between thyroid hormones sensitivity and cardio-metabo...

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ea0092ps2-11-06 | Miscellaneous 2 | ETA2023

Thyroid disorders in the faroe islands: incidence of hyperthyroidism, hypothyroidism, and structural abnormalities

Johannesen Herborg , Sofia Veyhe Anna , Feldt-Rasmussen Ulla , Krogh Rasmussen AEse , Linding Andersen Stine , Carle Allan , Andersen Stig

Objectives: Iodine intake affects the risk of thyroid disorders. This study aimed to calculate the overall incidence of thyroid dysfunctions and structural abnormalities in the Faroe Islands and to describe the relation to sex and age.Methods: We performed a nationwide, register-based study covering all 54,000 inhabitants of the Faroe Islands between 2006 and 2018. Cases were identified and classified by thyroid dysfunction using redeemed prescriptions o...

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ea0092ps2-11-07 | Miscellaneous 2 | ETA2023

Abstract withdrawn...

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ea0092ps2-11-08 | Miscellaneous 2 | ETA2023

Strange changes in thyroid hormone metabolism in post-covid patients in ajara

Jashi Liana , Peshkova Tamar , Kvanchakhadze Rusudan , Kamashidze Koba , Dundua Ketevan , Inaishvili Megi

Background: The pandemic has led to the development of strange and inexplicable disorders in various organs and systems, which do not fit into the existing standard of diagnosis and treatment of the disease. This was especially reflected in the metabolism of the thyroid gland. The aim of the study was to study the metabolism and changes of thyroid hormones in post-covid patients. (The study includes the results of two clinics)Materials and Methods: In th...

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ea0092ps2-11-09 | Miscellaneous 2 | ETA2023

Thyroid dysfunctions in covid-19 patients: impact on in-hospital outcomes and long-covid symptoms

Campi Irene , Lugaresi Marina , Battista Perego Giovanni , Fratianni Gerardina , Balla Eva , Bulgarelli Ilaria , Persani Luca , Fugazzola Laura

Context: A variety of thyroid disorders have been documented in COVID-19 patients, including non-thyroidal illness syndrome (NTIS), subacute thyroiditis (SAT) and thyrotoxicosis.Objectives: To investigate the relationship between thyroid dysfunctions observed during hospitalisation and COVID-19-related morbidity and mortality.Study design and setting: Prospective cohort study on patients admitted in a tertiary hospital for COVID-19...

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Endocrine Abstracts

45th Annual Meeting of the European Thyroid Association (ETA) 2023

Poster Presentations

Temporal pattern of thyroid function changes in patients with cured and not cured adrenocorticotropin (ACTH)-Dependent Hypercortisolism

Resistance to thyroid hormone alpha: outcomes of twelve years of thyroxine therapy

Evaluation of advanced end glycation products (AGES), their solube receptors (SRAGE) and the components of oxidative stress in patients with hashimoto’s thyroiditis on levothyroxine substitution

Behavior of thyroid function tests in a brazilian elderly population using big data

Sensitivity to thyroid hormones and cardiometabolic risk in euthyroid obese children: A cross-sectional study

Thyroid disorders in the faroe islands: incidence of hyperthyroidism, hypothyroidism, and structural abnormalities

Strange changes in thyroid hormone metabolism in post-covid patients in ajara

Thyroid dysfunctions in covid-19 patients: impact on in-hospital outcomes and long-covid symptoms

BiosciAbstracts