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45th Annual Meeting of the European Thyroid Association (ETA) 2023

45th Annual Meeting of the European Thyroid Association ETA 2023

Oral Session 6: Pregnancy

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Oral Session 5: Young Investigators / Basic
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Oral Session 7: Thyroid hormone receptors

ea0092op-06-01 | Oral Session 6: Pregnancy | ETA2023

Antithyroid drug exposure during 1,191,904 pregnancies in denmark: a 20-year longitudinal study before and after implementation of iodine fortification

Maria Uldall Torp Nanna , Liew Zeyan , Carle Allan , Scott Karmisholt Jesper , Bulow Pedersen Inge , Andersen Stig , Linding Andersen Stine

Objectives: Hyperthyroidism in pregnant women is a clinical concern, and it is important to surveil any change in the occurrence of hyperthyroidism within the pregnant population specifically, especially when a mandatory iodine fortification (IF) program is implemented as it was in Denmark in the year 2000. This longitudinal study aimed to investigate any change in the use of antithyroid drugs (ATD) for the treatment of hyperthyroidism in Danish pregnant women during a 20-year...
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ea0092op-06-02 | Oral Session 6: Pregnancy | ETA2023

Optimizing the dutch newborn screening for congenital hyothyroidism by using amino acids and acylcarnitines via a machine learning based approach

Jansen Heleen , van Haeringen Marije , Bouva Marelle , den Elzen Wendy , Bruinstroop Eveline , van der Ploeg Catharina , van Trotsenburg Paul , Zwaveling-Soonawala Nitash , Heijboer Annemieke , Bosch Annet , de Jonge Robert , Hoogendoorn Mark , Boelen Anita

Objectives: Congenital hypothyroidism (CH) is an inborn thyroid hormone (TH) deficiency mostly caused by disturbances at the thyroid level (thyroidal CH, CH-T). Less frequently, but equally important, CH can be the result of hypothalamic/pituitary dysfunction (central CH, CH-C). Most CH newborn screening (NBS) programs are based on the measurement of thyroid-stimulating hormone (TSH), thereby only detecting CH-T. The Dutch NBS detects CH by measuring total T4 concentrations in...
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ea0092op-06-03 | Oral Session 6: Pregnancy | ETA2023

Thyroid function in childhood is associated with sex, age, bmi, maternal thyroid function, pax8 gene methylation

Rossi Giada , Shirodkar Diksha , Silver Matt J. , Moore Sophie E. , Lazarus John H. , Hales Charlotte , N Taylor Peter , Ludgate Marian E. , Muller Ilaria , Candler Toby

Objectives: To assess antenatal and individual-level predictors of thyroid function across two longitudinal cohorts of children.Methods: Data were taken from two cohorts i) CATSII: 5-10 year-old children enrolled in the CATS (Controlled Antenatal Thyroid Screening) study II from the UK ii) ‘PAX8’: Children from the ENID (Early Nutrition and Immune Development) trial, a pregnancy and infant supplementation trial in The Gambia (Africa) recruited ...
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ea0092op-06-04 | Oral Session 6: Pregnancy | ETA2023

Changes in TSH suppression during pregnancy reveals novel mechanism for increased thyroid hormone production: comparison between euthyroid and thyroidectomized pregnant women

Scuto Andrea , Tumino Dario , Gambero Federica , Di Benedetto Guenda , Piticchio Tommaso , Malandrino Pasqualino , Frasca Francesco

Objective: Clarify mechanisms determining thyroid homeostasis during pregnancy at hypothalamic-pituitary level.Methods: Retrospective analysis of 251 pregnant women. 220/251 euthyroid without thyroxine therapy (Group 1), 31/251 thyroidectomized under thyroxine replacement therapy (Group 2). Patients under thyroxine replacement therapy with a TSH between 0.4 and 4.0 were included in the study. Patients with combined T3/T4 therapy were excluded.<p clas...
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ea0092op-06-05 | Oral Session 6: Pregnancy | ETA2023

The association of gestational thyroid function with gestational diabetes mellitus: an individual participant meta-analysis

Osinga Joris , Warringa Leonie , on Thyroid and Pregnancy working group on GDM Consortium , Derakhshan Arash , Korevaar Tim

Objective: Gestational thyroid dysfunction and gestational diabetes mellitus (GDM) are common complications during pregnancy and often co-occur. Since thyroid hormones increase glucose uptake and insulin sensitivity, it has been hypothesized that hypothyroidism might increase the risk of GDM. Our aim was to study if maternal thyroid function test abnormalities are risk factors for GDM.Methods: A systematic search of Ovid MEDLINE, EMBASE and Web of Scienc...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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