ECE2023 Poster Presentations Diabetes, Obesity, Metabolism and Nutrition (159 abstracts)
Epidemio-clinical and microbiological profile of Staphylococcus aureus bacteremia in diabetics
Nabil Lachiheb 1 , Bougharriou Ichrak 1 , Gargouri Omar 2 , Bartegi Ines 1 , Mnif Khouloud 1 , Hammami Adnene 2 , Mezghani Senda 2 & Ben Jemaa Mounir 1
1Hedi Chaker-Department of Infectious Deseases, Sfax, Tunisia; 2Habib Bourguiba Laboratory Of Microbiology, Sfax, Tunisia
Purpose: Diabetes is a major risk factor for Staphylococcus aureus (SA) bacteremia. The purpose of this work is to study the epidemiological, clinical and microbiological profile of SA bacteremia in diabetics.
Patients and methods: Retrospective study conducted in the infectious diseases department of Sfax between January 2003 and April 2022 (19 years), including all diabetics admitted for SA bacteremia (at least one positive blood culture).
Results: Among 166 patients admitted for SA bacteremia, 72 were diabetic (43.3%). They were 38 men and 34 women, with an average age of 53 ± 19 years. Associated risk factors were catheterism (n=27) and surgery (n=8). Bacteremia was community-acquired (n=38) and nosocomial (n=34). The portal of entry was mainly endovascular (n=29) and cutaneous (n=28). Septic localizations were noted in 37 cases (51.4%), mainly bone (n=17), muscle (n=10), lung (n=7), joint (n=7), kidney (n=6) and neurological (n=6). Community strains and nosocomial strains were resistant to methicillin in 18% and 29% respectively. Antibiotic susceptibility was for fusidic acid (81%), rifampicin (80%), gentamicin (80%), ciprofloxacin (78%) and cotrimoxazole (69%). The mean duration of antibiotic therapy was 54 ± 30 days. The evolution was favorable in 96%.
Discussion: SA bacteraemia is frequent in diabetics and is characterized by the multitude and variety of septic localizations. SA meti-R is relatively common in nosocomial and community settings. Early and appropriate antibiotic therapy often guarantees a good evolution.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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