ECE2023 Poster Presentations Thyroid (163 abstracts)
Assessment of sleep quality in patients in remission from differentiated thyroid carcinoma: a case-control survey
Abdel Mouhaymen Missaoui 1 , Fatma Hamza 2 , Siddiqa Soomauroo 1 , Khawla Ben Ahmed 2 , Wafa Belabed 1 & Mohamed Abid 1
1Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia; 2Habib Bourguiba University Hospital, Department of Nuclear Medicine, Sfax, Tunisia
Objective: To evaluate the quality of sleep in patients in remission of differentiated thyroid cancer (DTC)
Patients and Methods: Comparative case-control study conducted at the Nuclear Medicine Center of Sfax, Tunisia including 99 individuals divided into 2 subgroups G1 (n=39) patients in remission from DTC G2 (n=60) healthy control subjects Sleep quality was assessed according to the 7 components of the Pittsburgh Sleep Quality Index (PSQI)
Results: The mean sleep period was significantly shortened in G1 patients (06H:43’ vs 07H:05’; P=0.022). The duration of sleep in G1 patients was significantly longer than in the control group (41.5±35.4 vs 25.6±21.9 min; P=0.035). Subjective sleep quality (component 1), sleep latency (component 2) and sleep duration (component 3) were impaired in both groups. Sleep efficiency (component 4) is significantly lower for patients with DTC (P=0.000). G1 patients experience more sleep disturbances (component 5) (P=0.000). The use of sleeping pills (component 6) is significantly more frequent in G1. Sleep-related daytime dysfunctions (component 7) are comparable between the two groups. The global PSQI score was significantly higher in G1 (7.7±3.2 vs 5.9±2.8 points; P=0.049)
Discussion: Several sleep components are impaired in patients in remission from DTC compared to the general population. These patients frequently suffer from more disrupted and less compensatory sleep than normal subjects. Electro-physiological and neuro-hormonal studies are required to determine the mechanisms of these dysfunctions.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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