ECE2023 Poster Presentations Thyroid (163 abstracts)
Papillary Thyroid Carcinoma with Abdominal Desmoid-Type Fibromatosis – A Case Report
Klodiana Poshi 1 , Adela Haxhiraj 2 , Marjeta Kermaj 1 , Violeta Hoxha 1 , Dorina Ylli 2 , Florian Toti 1 , Tea Shehu 1 , Ardita Muja 3 , Adishah Çerma 1 , Ina Zotaj 3 & Agron Ylli 1,4
1UHC Mother Teresa Tirana, Endocrinology, Tirana, Albania; 2Salus Hospital, Endocrinology, Tirana, Albania; 2University of Medicine Tirane, Endocrinology, Tirana, Albania; 3Endocrinology, Tirana, Albania; 4Tirana Medical University, Tirana, Albania
Introduction: Papillary Thyroid Carcinoma is the most frequent malignant tumour of the thyroid gland. It usually progresses slowly and is rarely metastatic. On the other side, fibromatosis are usually benign tumours with infrequent malignant appearances, which affect musculoaponeurotic structures. The aetiology remains unclear, although various possible factors are linked to it such as trauma, genetic predisposition, β-catenin heterozygous mutation, hormone disbalance etc. Even though it benign status, fibramatosis are locally aggressive and can be associated with carcinomas of different kind such as the thyroid. Very few cases are reported in the literature of papillary thyroid cancer with mesenchymal tumours. We present the case of a patient with papillary thyroid cancer in concomitant with a desmoid-type fibromatosis abdominal tumour.
Case Report: The patient, a female of 31 years, came to the Department of Endocrinology after receiving the result of a biopsy. She had undergone total thyroidectomy on February 2020 for a diagnosis of multinodular goitre. The biopsy confirmed papillary thyroid cancer (classical variant) of 2 cm diameter, with capsular and vascular invasion. She was started hormone replacement therapy shortly after the surgery. Upon the arrival of the biopsy, she was planned for radioactive iodine therapy. She received 100 mCi. The patient had a prior surgery, on July 2019. She had an abdominal mass removed. The biopsy of it, supported by immunohistochemistry analysis later, resulted in abdominal desmoids-type fibromatosis. She had no family known history for neither of the diseases. The patient did not receive, apart from surgery, any other therapy for the abdominal tumour. At the time no genetics tests were performed. She is currently under examinations and regular follow-ups with no signs of recurrence.
Conclusions: The presence of both mesenchymal and papillary thyroid malignancy is a rare but present finding. Usually the thyroid is the first to be diagnosed, followed by the mesenchymal tumour, but it depends on the location and aggressive nature of the tumours. Considering the multiple possible factors in fibromatosis, it is important to further explore them in order to choose the better way of treatment and follow up.
Keynotes: thyroid carcinoma – fibromatosis – desmoids tumour - biopsy - surgery
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more