ECE2023 Eposter Presentations Thyroid (128 abstracts)
Thyroidectomy as a treatment of graves’ disease in children
Mohamed Masmoudi , Chaima Zitouni , Wadii Thabet , Ezer Chebil , Mehdi Hasnaoui & Khelifa Mighri
Taher Sfar Hospital, ENT Department, Mahdia, Tunisia
Introduction: Graves’ disease (GD) accounts for 10%-15% of thyroid disorders in children and adolescents.
Material and Methods: We report the clinical, therapeutic aspects and long-term results of 9 children (<18 years) who had for Graves’ disease, from 2000 to 2021.
Results: The mean age at diagnosis was 15,8 years [9 – 18 years]. Our study included 3 boys and 6 girls. One patient had coeliac disease. The surgery was conducted because of failed 2-year medical therapy in 5 cases and compressive goiter in 4 cases. Total thyroidectomy was performed in all cases. The postoperative course was complicated by transient hypocalcemia in one case. After an average follow-up of 5 years, all patients had control of the disease clinical manifestations including Graves’ ophthalmopathy and biological euthyroidism.
Conclusion: The use of antithyroid drugs as the initial treatment option in Graves’ disease is well accepted. An average two years remission is achieved in about 30% of children. Otherwise, radio-iodine therapy and surgery are considered as treatment options. Compared to surgery, radioiodine therapy can increase the risk of cancer and cause worsening of Graves’ opthalmopathy, especially in children. Therefore, surgery may be a better option.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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