Endocrine Abstracts

Introduction: Polycystic ovary syndrome is a very heterogeneous disease. Clinical and para clinical findings in such patients varies from one patient to another.

Aim: The aim of our work is to study the clinical and para clinical profile of PCOS.

Methods: This is a retrospective descriptive study of patients with PCOS followed in the endocrinology department of Hedi Chaker University Hospital of Sfax, Tunisia. PCOS +was diagnosed based on the Rotterdam Consensus definition.

Results: We collected 50 patients. The average age was 24.56 years +/- 6, 5. Subfertility was objectified in 64.7%. Family history of PCOS was reported in 10% of cases. The mean BP was 120/100 mmHg. The mean body mass index was 32.39 +/- 8.93, this could be related to the lack of physical activity (2% were actif). Despite that, only 7 women were obese. Hirsutism was noted in 85% of cases. However, the average of testosterone was at 0,66. Mean FSH, LH and estrogen levels were respectively 5.16, 10 and 52, 62 UI/ml. We have noted that 38 patients had spaniomenorrhea. Microcystic ovaries were reported in 68% of cases. The lipid balance total cholesterol levels varied between 3.22 mmol/l and 12.41mmol/l with an average of 5.12 mmol/l. We have also recorded blood sugar levels in the average of 5.6 mmol/l with a glycated hemoglobin at 5.9 % and mean insulinemia at 12,38 UI/ml.

Discussion: Until today, no consensus for the management of PCOS. Thus, a better understanding of the PCOS is necessary for a structured and well codified management. A study on a larger number of patients is recommended to better study the variability of the clinical and paraclinical profile of PCOS.