ECE2023 Eposter Presentations Reproductive and Developmental Endocrinology (48 abstracts)
Serum AMH levels and insulin resistance in women with Hashimoto thyroiditis
Agnieszka Adamska 1 , Angelika Buczyńska 2 , Marta Olszewska 1 , Justyna Łapińska 1 , Aleksandra Łobacz 2 , Katarzyna Winnicka 1 , Katarzyna Siewko 1 , Anna Popławska-Kita 1 & Adam Krętowski 1,2
1Medical University of Białystok, Department of Endocrinology, Diabetology and Internal Medicine, Białystok, Poland; 2Medical University of Białystok, Clinical Research Centre, Białystok, Poland
Objective: Women with Hashimoto thyroiditis (HT) could have fertility problems. Serum anti-Müllerian hormone (AMH), which reflects functional ovarian reserve, is decreased in women with HT. The aim of the present study was to investigate the relation between serum levels of AMH and insulin resistance in women with HT compared to control group.
Patients and methods: We examined 193 women: 37 subjects with HT, without previous history of treatment with L-thyroxin, and 156 control women. Serum concentrations of AMH, TSH, thyroid hormones, insulin, glucose, HbA1c, lipids were assessed. HOMA-IR was calculated.
Results: We did not observed differences in serum concentration of AMH in women with HT in comparison to the control group (P=0.26). We also did not noticed differences in serum levels of TSH, thyroid hormones, glucose, insulin, HOMA-IR, HbA1c and lipids between studied groups (all P> 0.05). In women with HT, we observed relationships between serum levels of AMH and insulin (r=0.34, P=0.03), we also observed that AMH levels was connected with HOMA-IR (r=0.36, P=0.02) in women with HT. However, we did not find relation between serum concentration of AMH and HOMA-IR in the control group (r=-0.03, P=0.68).
Conclusions: We observed in women with HT connection between insulin resistance and marker of functional ovarian reserve.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more