Endocrine Abstracts

Background: Acromegaly which is caused by excessive growth hormone is a rare chronicle endocrine disorder. Because it is a rare disorder, limited data are available on the impact and consequences of acromegaly on the mental health of patients, but the investigations are growing over time.

Aim: It aims to summarize the evidence identifying the mental health issues of patients with acromegaly.

Methods: MEDLINE (PubMed), Web of Science, and CINAHL databases were searched to retrieve potential studies from January 2000 to December 2022. Two reviewers independently screened abstracts, following specific eligibility criteria.

Findings: According to the studies, the main mental health issue was decreasing the quality of life of the patients. Other mental health issues were having depressive symptoms and mood swings, feeling of burden, impairments in body-self-perception, disruption in interpersonal relations, decrease in sleep quality, and social withdrawal anxiety.

Conclusion: Overall, the findings of this review suggest that there are many different mental health issues among patients with acromegaly which emphasize holistic health care. Also, the number of psychological interventional randomized controlled studies should be increased.

Keywords: acromegaly, mental health, quality of life