ECE2023 Eposter Presentations Adrenal and Cardiovascular Endocrinology (124 abstracts)
Characteristics of Hypertension in patients with pheochromocytomas
Sahar Abidi , Sabrine Mekni , Sawsen Essayeh , Wafa Ben Hilel , Cherchir Faten , Nadia Mehuirgui , Ibtissem Ben Nacef , Imen Rojbi & Karima Khiari
Charles Nicolles Hospital, Endocrinology Department, Tunis, Tunisia
Introduction: Pheochromocytomas are rare catecholamine-secreting tumors presenting with various clinical manifestations. Hypertension is the most common finding in pheochromocytomas. It can be either persistent or paroxysmal. Study Design: We conducted a retrospective study of 34 patients who were admitted into the endocrinology department of Charles Nicolle hospital, with a diagnosis of a pheochromocytoma from January 2005 to November 2022.
Results: Twenty one patients (64%) had a family history of hypertension. Nine patients (27%) had diabetes and eight patients (25%) had dyslipidemia. Twenty six patients (77%) had hypertension. The median of years with hypertension was 3.5 years IQR (1-5,7). The mean number of used antihypertensive drugs was 2.4 ±1.3 [extremes:1-6]. Two patients had coronary disease and one patient had heart failure. An ultrasound myocardium imaging was practiced in 22 patients. Myocardial amyotrophy was detected in 36% of cases (eight patients). Five patients had electric EKG abnormalities. Hypertensive retinopathy, microalbuminuria and chronic kidney disease were detected in 18, 93 and 20% of cases, respectively. Surgical treatment was performed in 27 cases (93%). Fifteen (56%) patients were cured of their hypertension after surgery.
Conclusions: Pheochromocytomas are considered as one of the most common causes of curable hypertension. Early diagnosis of theses tumors is important, owing the possibility of curing hypertension and preventing its lethal complications.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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