ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Why not MODY monogenic diabetes? A case report
Salma Mohsen , Chaima Jemai , Hana Ben Jemaa , Dorra Ben Selem , Skander Msolly , Zohra Hadj Ali , Yosra Htira , Imen Hedfi & Feika Ben Mami
National Institute of Nutrition of Tunis, C, Tunis, Tunisia
Introduction: Monogenic diabetes MODY is common but remains under diagnosed because genetic study is expensive in our country.
Method: We report the case of an 18-year-old patient with no personal pathological history admitted in October 2022 for diabetes management. Her diabetes was diagnosed accidentally on July 2022: Systematic capillary blood glucose done when she had a Hysteria’s crisis revealed values higher than 2 g/l. From July to October, the patient did not received any antidiabetic treatment and never had any acute complication, especially ketoacidosis one. Our patient did not have cardinal signs of diabetes. The physical examination showed acanthosis nigricans and overweight (BMI=25.7 kg/m2). HbA1c was 9.9%, insulinemia and C-peptide were normal, and HOMA index was 2.52. Thyroid parameters and basal cortisolemia were normal. There were no pancreatic autoimmunity (negative anti-GAD 65, anti-islets and anti-insulin antibodies). The “MODY RISK” score was at 75%. The association of polycystic ovary syndrome or polycystic kidney disease was ruled out by radiological examinations. The patient was put on Glimepiride 1 mg/d and Metrormine 850 1 cp/d with achievement of glycemic targets. The genetic study was requested in progress.
Conclusion: Monogenic diabetes MODY has common characteristics with T1D and T2D. It is often underdiagnosed due to the cost of genetic study but it should be evoked when diabetes presentation is atypical.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more