Endocrine Abstracts

Aim: To study the role of chronic kidney disease (CKD) for cardiovascular outcomes in patients with DM 2

Material and methods: 50 male patients (average age from 40 to 65 years) were identified at the time of diagnosis of DM2 with CRS from the databases of the department of diabetic nephropathy of the Center of Endocrinology named by Acad. Yo.Kh. Turakulov for the period 2022. Patients were under supervision after the diagnosis of adverse cardiovascular events – ACE- (myocardial infarction, stroke, AG, mortality), heart failure (HF) and CRC. Patients were distributed to 2 groups: 1 group – these are patients with DM2+ CKD (24 patients), 2 group – DM2+ CKD + HF + hypertension + hyperlipidemia (26 patients)

Results: CKD was associated with a higher risk of HF, mortality and ACE. This risk was more pronounced in elderly patients with the ACE in the history. (P <0.05). When analyzing in a general cohort in patients with DM2+ CKD + HF + hypertension + hyperlipidemia, the risk of the frequencies of the ACE was increased, HF compared to patients with DM2+ CKD. (P <0.05)

Conlusion: In patients with DM2, the presence of CKD was associated with a higher risk of ACE, HF and mortality.