ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Association of ABO blood groups with diabetic microvascular complications
Sevgul Faki 1,2 , Nurcan Ince 2 , Abbas Ali Tam 2 , Beril Turan Erdogan 2 , Neslihan Çuhacı Seyrek 2 , Oya Topaloglu 2 , Reyhan Ersoy 2 & Bekir Cakir 2
1Ankara City Hospital, Departments of Endocrinology and Metabolism, Ankara, Turkey; 2Ankara Yıldırım Beyazıt University, Faculty of Medicin, Departments of Endocrinology and Metabolism, Ankara, Turkey.
Background: Micro vascular complications are the major outcome of Type 2 Diabetes Mellitus progression, which reduces the quality of life and increases diabetic morbidity & mortality. As the incidence of type 2 diabetes is growing day by day; our search for its aetiology and pathogenesis is also ever growing to predict its risk factors and early screening for better care and prevention of its complications. Many studies have tried to link susceptibility of type 2 diabetes with ABO blood group though results have been inconsistent. The present study aims to analyse association of micro vascular complication with different blood groups if any.
Methods: The study included the paitents with diabetes who were hospitalized and followed up in our clinic form Dec. 2019 to April 2022. Information such as age, sex, and family history of diabetes was scanned from medical records. The blood group was determined by standard serological methods. Screening of microvascular complications done by appropriate clinical examinations and laboratory investigations.
Results: There was 348 patients with type 2 diabetesin this study, the average age of the patients was 59.3±12.8, male to female ratio was 142(40.8%)/204 (59.8%) reapectively. 246 (70.68%) patients had one or the other complications. Diabetic nephropathy, rethinopathy and neuropathy ratio was 31.3%, 35.20% ve %52.0% respectively. None of the type of micro vascular complication was found to be significantly associated with different blood groups. In addition we found that Rh (−) group had significantly low Diabetic nephropathy, rethinopathy compare to Rh (+) group (P=0.044 ve P 0.041).
Conclusions: Although we didn’t finde a relationship between ABO blood group and diabetic microvascular complications, Rh (+) was found to be a risk factor for developing nephropathy and retinopathy.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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