ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Can prebiotics improve weight loss in obese patients?
Rym Ben Othman , Zeineb Zemni , Chaima El Ghali , Wafa Douiri , Berriche Olfa , Ramla Mizouri , Nadia Ben Amor , Faten Mahjoub & Jamoussi Henda
National Institute of Nutrition of Tunis, Obesity Research Unit, Bab Saadoun, Tunis, Tunisia.
Background: Prebiotics are compounds in food that induce the growth of beneficial microorganisms such as bacteria and fungi, which are essential for the proper functioning of the microbiota. The objective of our work was to evaluate the effect of prebiotics intake on anthropometric parameters in addition to a weight loss program.
Methods: This is an interventional study involving 30 obese patients consulting the obesity unit of the Institute of Nutrition of Tunis during the period from May to August 2022. Patients were divided into 2 groups matched for age, sex and BMI: diet alone and prebiotics (30 g of carob/d). Anthropometric measures (weight, waist circumference, BMI), body composition, and muscle strength (using handgrip dynamometer) were assessed at T0 and at one month after the intervention (T1).
Results: The mean age was 40.3±6.7 years with a female predominance (80% of women). For the diet alone group, there was a significant decrease in body weight (−2.5 kg, P=0.001), BMI (−0.9 kg/m2, P=0.001) and waist circumference (−1.7 cm, P=0.01) between T0 and T1. For the prebiotic group, in addition to the significant decrease in weight (−2.2 kg, P=0.003), BMI (−0.9 kg/m2, P=0.001) and waist circumference (−4 cm, P=0.03), we have noticed a significant decrease in fat mass (−2.9 kg, P=0.001) and percentage fat mass (−1.8%, P=0.001), as well as a significant improvement in muscle strength (+1.4 kg, P=0.008). Although the decrease in body fat and body fat percentage and the increase in muscle strength were significant in the prebiotic group and not in the diet alone group, the difference between the two groups was not significant.
Conclusion: For anthropometric parameters, the prebiotic group was not superior to the diet alone group.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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