Endocrine Abstracts

Aims: Screening for celiac disease in adult type 1 diabetics and studying its clinical and paraclinical profile.

Patients and methods: Cross-sectional descriptive study conducted among 150 adult type 1 diabetic patients followed in Department A of the National Institute of Nutrition of Tunis. All patients underwent serological screening for celiac disease.

Results: The prevalence of histologically confirmed celiac disease was 3.33% while 4% had positive celiac disease serology. The average age of patients with celiac disease was 34.8 years with an average BMI of 22.71±2.76 kg/m² and four out of five patients had a normal BMI and diabetes evolving for more than 5 years. Three out of five patients had uncontrolled diabetes and two had recurrent hypoglycaemia. Among the five diabetics with confirmed celiac disease, only one patient showed classic signs of celiac disease. Of the others, one patient was asymptomatic and three showed non-classical signs of celiac disease.

Discussion: The recommendations of the various learned societies on the methods of screening for celiac disease in adult patients with type 1 diabetes are still controversial, hence the need for more studies on this subject [1-7].

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6. Rubio Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA, American College of Gastroenterology. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol. 2013;108(5):656–767.

7. National Institute for Health and Clinical Excellence. Coeliac disease: recognition and assessment of coeliac disease [En ligne]. NHS [cité le 26/01/2022]; [environ 86 écrans]. Disponible à l’URL: http://www.ncbi.nlm.nih.gov/books/NBK11690/