Endocrine Abstracts

Introduction: Peripheral arterial disease (PAD) is a classic localization of macroangiopathy in diabetics. It is a major risk factor for amputation.

Goal of the Study: know the prevalence and analyze the risk factors associated with peripheral arterial disease.

Patients and Method: Descriptive and analytical retrospective study conducted in the department of endocrinology and metabolic diseases of the CHU Ibn Rochd, where 544 asymptomatic diabetic patients were screened for peripheral arterial disease. PAD was defined by an ABI measurement less than 0.9 or greater than 1.3.

Results: A total of 544 patients were included in our study, 65.6% of whom were women. The average age of our patients was 51.2 years (15-89). Type 2 diabetes predominated in 80.5% of cases with an average duration of evolution of 10.6 years and an average HbA1c of 10.1%. The prevalence of PAD was 21.7%. The risk factors significantly associated with PAD were: advanced age (P=0.001), hypertension (P=0.002), dyslipidemia (P=0.002), physical inactivity (P=0.002), coronary artery disease (P= 0.001), a history of stroke (P=0.027), the presence of micro albuminuria (P=0.001), retinopathy (P=0.001) and diabetic neuropathy (P=0.000). On the other hand, neither tobacco nor obesity was linked to PAD.

Conclusion: The prevalence of PAD is high in diabetics. These results encourage systematic screening and rigorous follow-up of high-risk patients and to include control of cardiovascular risk factors and glycemic control in management strategies.