Endocrine Abstracts

Introduction: We already know that smoking is one of the causes of type 2 diabetes. Cigarette smoking increases the risk for type 2 diabetes incidence and is an independent risk factor for type 2 diabetes. Nicotine in tobacco is responsible for the association between cigarette smoking and development of diabete.

Aim: The purpose of this study was to evaluate the impact of smoking on the course of type 2 diabete.

Material and Methods: A total of 191 patients were included in the study, divided into four groups based on whether they smoked or not and on medication. Group 1: smoking (n=39), Group 2: non-smoking (n=153), Group 3: treatment of diabetes drugs (n=77), group 4: treatment of insulin (n=114).

Results: The mean age of 62.23±10.85 years (43-82 years) with a sex ratio (M/F) of 0.94. The majority were 114 patient (59.6%) type 2 diabetics treatment of insulin and 77 patient (40.3%) treatment of diabetes drugs. The mean age of diabetes was 9.74±4.23 year (0:30). The mean HbA1C was 8.35±6.59% (4.8-13.3%). Obesity was present in 56.4% of patients. The incidence of hyperuricemia was 21.8%. In ours study were noted smoking in 39 patient (20.4%) of cases of wich 28 patient (71.7%) were men and 11 patient (28.2%) were women. 27 patient (69.2%) in treatment of diabetes insulin and 12 patient (30.7%) patient in treatment of diabetes drugs. The mean HbA1C of smoking patients was 8.55±4.04% (4.6-12.2%). Diabetes was found to be balanced in 18 patient (46.1%) smoking of wich 12 patient (66.6%) in treatment of diabetes insulin with HbA1C 6.86±3.70% (4.6-7.5%) and 6 patient (33.3%) smoking in treatment of diabetes drugs with HbA1C 6.94±3.72% (5.7-7.5%). The mean HbA1C it was not comparable between the two smoking groups.

Conclusion: Smoking increases not only the risk for type 2 diabetes mellitus but there is also has an impact on its progress. Our study showed that individuals with type 2 diabetes mellitus and smokers had a poor course of diabetes compared to non-smoking individuals with type 2 diabetes mellitus and smoking individuals treated with insulin had better progress than those treated with drugs.

Keywords: Smoking, non-smoking, insulin, drugs.