ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Glycosylated haemoglobin levels in new and known diabetes patients with hyperglycaemic ketoacidosis
Safouane Charfi 1 , Rim Marrakchi 1 , Ksentini Mohamed 1 , Mariem Boudaya 1 , Kamel Jamoussi 1 , Mouna Turki 1 , Faten Haj Kacem Akid 2 & Mohamed Abid 2
1Hedi-Chaker University Hospital of Sfax, Biochemistry Departement, Sfax, Tunisia; 2Hedi-Chaker University Hospital of Sfax, Endocrinology Departement, Sfax, Tunisia
Background/Aims: Ketosis in patients with known Type 2 diabetes mellitus is overlooked due to atypical symptoms. Type 2 diabetes (DT2) is characterized by a longer period of asymptomatic hyperglycaemia than Type 1 diabetes(DT1). The objective of this study was to compare glycosylated haemoglobin (HbA1c) levels in ketoacidosis (DKA) occurring in known and newly diagnosed diabetes.
Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between November 2021 and January 2022. HbA1c levels were determined on ADAMS ® Arkray at presentation. The data were analyzed using SPSS 26.
Results: There were 14 known DT1 or DT2 patients and 6 newly diagnosed diabetes. The mean age was 24±8.30 years The mean HbA1c of all admissions was 12.03±2.96% (n=20) . The mean HbA1c in known DT1 or DT2 and newly diagnosed diabetes patients were similarly high 11.6±3.2% and 13.6±1.6% (P0.15 ) respectively. The averages of HbA1c above 8% were statistically similar in the both groups of patients (93.3% in known DT1 or DT2 vs 100% in newly diagnosed diabetes patients.
Conclusions: DKA is associated with markedly elevated HbA1c levels in known DT1 or DT2 and new onset diabetes.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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