Endocrine Abstracts

Purpose: The purpose of the study is to evaluate the results of MRI of studies in patients with the active stage of the Charcot foot.

Material: The material of the study 29 patients (prospectively) were examined with type 2 diabetes with the active stage of the Charcot foot in the period 2021 at the RSSNPMC of endocrinology, in the department of diabetic foot. The control group amounted to 20 healthy persons.

Background/Aim: Biochemical (bilirubin, straight, indirect, lipid spectrum, ALT, AST, Coagulogram, blood sugar, glycated hemoglobin, urea, creatinine). Instrumental: ECG, MRI, Dopplerography of the main vessels of the legs, ultrasound of internal organs, DEXA, ocular fundus.

Research Results: In the patient’s group, 21 men were observed (the average age of 69.6 years) and 8 women (the average age 68, 9 years). The duration of the DM2 was 21/19, respectively\. The duration of the SDS was 9/7 years, respectively. On MRI we found location of bone marrow abnormality (edema shown in fluid sensitive sequences, and reduction of fatty bone marrow shown in T1 sequences). Pattern tends to be periarticular. In all patients were involved several joints and bones (mostly tarso-metatarsal joints and metatarsophalangeal joints).

Conclusions: During early-stage Charcot foot, CT does not play an important role for imaging since bone marrow and soft tissue changes can be better visualized using MRI. CT may be used in later-stage Charcot foot for better visualization of bony proliferations and consolidation. Recognizing this disease in early stages prevents a delayed onset of an appropriate therapy and helps minimizing the disability of these patients.