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Endocrine Abstracts (2023) 90 EP264 | DOI: 10.1530/endoabs.90.EP264

Institut De Nutrition, Tunis, Tunisia


Introduction: Hypoglycaemia is the most common metabolic complication in type 1 diabetes. Although rarely dangerous, it significantly impairs quality of life. The aim of our study was to determine the prevalence and factors associated with hypoglycaemia in T1DM.

Methods: Descriptive cross-sectional study conducted over 3 months in ward C of the Institute of Nutrition, which included patients with type 1 diabetes.

Results: Fifty-seven patients were included, of whom 31 were women and 26 men. The characteristics of the patients were respectively: age: 32.3±9.6 years, BMI: 23.16± 3.1 kg/m2, HbA1c: 10±2.2%, duration of diabetes: 16.1±8.8 years, duration of insulin therapy > 10 years: 65%. Forty-two patients were on human insulin and 15 patients on insulin analogues. Of these, 78% were on basal/bolus plus. 72% of our patients had at least one episode of hypoglycaemia in the previous 6 months. The frequency of hypoglycaemia was correlated with the length of time the patient had diabetes (P=0.02), the number of insulin injections per day (P=0.013) and with gender, with women having more hypoglycaemia than men (P=0.028). Moreover, the higher the frequency of hypoglycaemia, the higher the HBA1C (P=0.031). However, there was no statistically significant correlation between the prevalence of hypoglycaemia and chronic degenerative complications of diabetes.

Conclusion: In T1DM patients, the predictive factors for hypoglycaemia are: female gender, duration of diabetes, duration of insulin treatment and number of injections.

Volume 90

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

European Society of Endocrinology 

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