Endocrine Abstracts

Introduction: Maternal diabetes is described as a risk factor for neonatal hypocalcemia along with maternal vitamin D deficiency or maternal hyperparathyroidism. The frequency of hypocalcemia in a diabetic mother is 20 and 60%, but low in gestational diabetes (GD).

Observation: A 38 year old female patient, with a pregnancy estimated of 35 weeks of gestation, was referred to our department for the management of her gestational diabetes, her cycle was very unbalanced, and her general check-up was without any particularity, especially her phosphocalcic balance. The patient was put on insulin therapy with good evolution, 2 Weeks later; the patient gave birth to a girl with neonatal hypocalcemia.

Discussion and Conclusion: Diabetes is a pathology with fetal and neonatal risk of varying severity. The mechanism of occurrence of neonatal hypocalcemia, its pathophysiology is still unknown today. Studies have established a link between the risk of hypocalcemia in the neonatal period and the maternal glycemic control observed during pregnancy. There is an association between the degree of severity of diabetes and the blood glucose level at birth. The prognosis is better in the case of GDM, especially if it has remained balanced throughout the pregnancy.