ECE2023 Eposter Presentations Calcium and Bone (99 abstracts)
1Habib Bourguiba Hospital, Department of Otolaryngology (ENT) Head and Neck Surgery, Sfax, Tunisia, 2Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia
Aim: The purposes of our study are to study the effect of systematic calcium and vitamin D supplementation on parathyroid glands function after total thyroidectomy.
Patients and Methods: We conducted a prospective cohort study, including patients undergoing total thyroidectomy. Patients were randomly divided into two groups: group 1: with prophylactic supplementation (24 patients) and group 2: without prophylactic supplementation (23 patients). For each patient, undergoing total thyroidectomy, the assessment includes Ca; PTH in preoperatively and at day 1 and day 30 on postoperative.
Result: The mean PTH on day1 for group 1 was 12.7 pg/ml±10.7 and 17.4 pg/ml±7.5 for group 2. The difference was not statistically significant (P=0.09; Students T-test for independent sample). The mean PTH at day 30 for group 2 was 23.4 pg/ml±15.7 and 25.7 pg/ml±9.7 for group 1. We did not notice any difference in mean PTH between the two study groups. (P=0.54; Students T test for independent sample)
Conclusion: Calcium and vitamin D supplementation has no inhibitory effect on PTH on D1 and D30 and therefore does not in any case delay the resumption of parathyroid glands function. In addition, it appears in our study that this supplementation improves parathyroid function at 1 month.