Endocrine Abstracts

Introduction: Obesity and vitamin D deficit are risk factors for inflammation, insulin resistance, hypertension and impeded bone mineralization and also cardiovascular disease. type 2 diabetes and osteoporosis. As globally both conditions reach pandemic levels and the level of vitamin D negatively correlates with obesity we studied this correlation and impact on a group of children suffering from obesity.

Materials and method: We conducted a retrospective ecologic correlational study on 71 children from the south of Romania, who attended our nutrition clinic from 2020-2021, with the age median=12, median BMI=27, median obesity degree 145%.

Results and conclusion: A deficit of vitamin D was found in 31 patients (43.66%), 38.02% with mild deficit and 5.63% severe deficit. The vitamin D deficit positively correlates with the obesity degree (t value =30,45, P< 0.00001) and the percent of body fat (t value=26.96, P< 0.00001) Vitamin D deficit is present in nearly half of the children from the group, with deficit levels that statistically positively correlate with the degree of obesity and percent of body fat. Obesity is associated with a resistance to vitamin D supplementation and a new guideline for the substitution of vitamin D in this population as doctors still prescribe doses as for normal weight children. Keywords: pediatric obesity, vitamin D, body fat, deficit.