Endocrine Abstracts

The aim of the study is to identify the frequency of occurrence of various morphological types and various degrees of severity of anemia in patients with Graves disease(GD).

Material and methods: The data of the case histories of 157 patients operated on for GD in 2012 were analyzed. When assessing hematological parameters, two groups were identified: Group 1 - patients with GD with mild anemia (n= 98), age 39.4 ± 1, 4, men - 41 (41.8%), women - 57 (58.2%) and group 2 - patients with GD with moderate anemia (n= 59), age 41.1 ± 1.7, men - 11 (18.6%), women - 48 (81.4%). In the clinical analysis of blood, hemoglobin, hematocrit, erythrocyte count and erythrocyte indices MCV, MCH, MCHC were determined.

Results: Microcytic type of anemia was observed more often with moderate severity of anemia (89.8%), and normocytic type of anemia was detected more often with mild anemia (12.2%). Hypochromic and normochromic types of anemia were detected with the same frequency in mild and moderate anemia (hypochromic in 94.9%, normochromic in 5.1%,)

Conclusion: GD is characterized by a high incidence of anemia, more often of mild severity (62.4%), microcytic (88.5%) and hypochromic (94.9%), due to iron deficiency.