ECE2023 Eposter Presentations Thyroid (128 abstracts)
Safety and Efficacy of Radiofrequency Ablation of Thyroid Nodules. Our Experience With A Cohort of 43 Patients
Blanca Bernaldo Madrid 1 , Sara Mera Carreiro 1 , Patricia Espinosa De Los Monteros 1 , Fernando Hernández Olmeda 1 , Laura Avila Anton 1 , Noelia Sánchez-Maroto García 1 , Salomé Merino 1 , Celia Lopez Nevado 2 , Mario Pazos Guerra 1 & Maria Cristina Familiar Casado 1
1Hospital Clinico Universitario San Carlos, Madrid, Spain, 2Hospital Central de La Defensa Gómez Ulla, Madrid, Spain
Introduction: The majority of current guidelines recommend surgery for benign solid nodules with pressure symptoms or a significant growth. Currently, minimal invasive techniques have emerged such as radiofrequency ablation (RF) which achieve significant volume decrease and many cases, the improvement or disappearance of pressure symptoms.
Results: We describe the efficacy and safety of one single-session of RF in our centre performed in thyroid nodules from 43 patients (8 men) with a mean age of 58,6± 13 years. Only nodules with a minimum follow-up of 6 months were included (range 6 months to a maximum of 2 years in 28 cases). Half of the patients had a multinodular goiter and only 3 patients were on previous treatment with antithyroid drugs. Mean plasma thyroid hormone levels were 1.75 ± 1.13 mU/l for TSH 8.7 ± 1.34 pg/ml for T4. The mean nodular volume was 21.6 ± 13.4 ml before the procedure. The indications for RF included: pressure symptoms in 37.2% of patients, nodule growth in 48.8% and both criterion in 14% of cases in patients who refused surgery. After RF, transient minor complications (local pain, bleeding) were registered in 46,8% of cases and one patient presented a major complication consisting in a nodule rupture which resolved spontaneously. During the follow-up, mean volume decreased significantly since the first month (14.1 ± 10.7 ml) achieving a value of 9.9 ± 9.1 ml at the 3rd month; 8.35 ± 7.95 ml at the 6th month; 8.5 ± 8.9 ml at the first-year y 7.7 ± 9,6 ml at the 2nd year. The percentage of ablation success (defined as decrease >50% nodular basal volume) also increased progressively: 25,6% (n=42) at the first month, 53,5% (n=40) at month 3 and 60,5% (n=39) at month 6. Pressure symptoms disappeared in all but one patient. Surgery was needed in 7 cases (16,2%), in half of the cases due to RF failure and subsequent nodule growth.
Conclusion: RF is a safe and effective alternative to surgery in patients with pressure symptoms or significant nodule thyroid growth.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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