Endocrine Abstracts

Nonalcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease in children and adolescents in the United States, disproportionately affecting certain ethnic and racial groups. A 2 to 3-fold rise in the prevalence of obesity and overweight in children over the last 3 decades highly relates to the NAFLD epidemic. There are concerns that children with nonalcoholic steatohepatitis (NASH) are more prone to progress to cirrhosis, which may increase li...

Obesity is defined as excess body fat mass with adverse health consequences and is a chronic disease often associated with co-morbidities when it persists into adulthood. It is therefore important to support adolescents with obesity during the period of transition to adulthood in order to avoid the possible worsening of their medical condition. This risk is particularly important in the specific case of monogenic or syndromic obesities, especially as it is also a period of fra...

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